Contributes To The Normal Function Of The Heart

Clinically tested food supplement DHA omega-3 250 mg; lycopene 7 mg Supported by Delligent™ Technology

Lycodha is a unique, clinically tested combination of DHA omega-3 and lycopene formulated with the use of patent-pending Delligent™ Technology. Developed in Cambridge, UK, Delligent™ Technology enables intelligent delivery of critical nutrients to their intended points of action using proprietary purpose-designed chaperone formulation. Lycodha is delivered and active in the liver and subsequently in lipoproteins, where DHA omega-3 and lycopene combine to demonstrate a significant beneficiary effect of improvement of key cardiovascular risk biomarkers

DHA omega-3 and Lycopene

Lycodha contains a Delligent™ combination of DHA omega-3 and carotenoid lycopene that help maintain the normal function of the cardiovascular system by contributing to healthy lipid levels, specifically triglycerides and help control the oxidation of LDL lipoproteins.

DHA omaga-3

The beneficial ingredients of fish oils are known as omega-3 fatty acids, consisting of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) which belong to the group of Polyunsaturated Fatty Acids (PUFA). Mammals have limited capability to synthesize omega-3 fatty acids. Therefore, these essential micronutrients need to be delivered through diet.


It is a carotenoid from the class of plant pigments that provide the bright red, orange and yellow colours of many fruits and vegetables. Lycopene helps control the oxidation of LDL cholesterol, one of the main contributors to an increased risk of cardiovascular disorders.

The unique combination of active ingredients, bioavailability, bioactivity tests and proprietary production technology makes Lycodha the most advanced form of DHA omega-3 cardiovascular preventive supplementation.

Delligent™ Technology

Delligent™ Technology is a patent pending intelligent delivery system that enables the delivery of the active ingredient directly to the point of action through influencing the absorption route of lipophilic compounds. The use of proprietary chaperone composition can enhance or reduce liver dependent effect on ingested actives.

Using Delligent™ Technology's unique chaperone system, Lycodha is transported via the liver where it has been proven to work most effectively on key cardiovascular biomarkers, including the reduction of triglyceride synthesis in the liver and the induction of peroxisomal β-oxidation.

There are two possible routes of lipophilic ingredients absorption:

  • via the portal vein to the liver, or
  • through the lymphatic system directly to systemic blood circulation and to other tissues.

Delligent™ Technology allows for the optimization of the absorption route of the compound, depending of its intended point of action.

Regular omega-3 fatty acids are mostly incorporated into large chylomicrons and directed to lymphatic system through the lactic duct and subsequently to the systemic blood circulation.

Adding appropriate Delligent™ chaperone composition can increase the portal vein absorption and in effect direct liver delivery of Essential Fatty Acids.

The omega-3 fatty acids triglycerides reduction activity is localized mostly in the liver. These include the reduction of triglycerides synthesis, reduction of triglycerides incorporation into VLDLs and induction of beta oxidation processes, which increase fatty acids utilisation in energy production processes.

Therefore, Delligent™ Technology, through enhancing portal vein absorption and liver delivery of DHA omega-3 and lycopene, significantly enhances its activity related to triglycerides reduction and lipoproteins oxidation reduction

What are Delligent™ Chaperones

Delligent™ chaperones consist of optimally selected fatty acids (with regards to their chain length and saturation level) and carotenoids (with regards to their level of polarity).

How Lycodha Supports Cardiovascular Health

Cardiovascular Disease (CVD) is the #1 cause of death globally. Most CVDs can be prevented by addressing behavioural and life style related risk factors such as tobacco use, obesity, physical inactivity and harmful use of alcohol.

Another factor in cardiovascular health is diet. Populations in countries that have a traditional diet with a high consumption of oily fish have a 10% lower rate of CVD mortality*, despite their high dietary fat intake. The protective ingredients of fish oils are known as omega-3 fatty acids, belonging to the group of Polyunsaturated Fatty Acids (PUFA). They can improve a broad range of cardiovascular risk factors including plasma triglycerides concentration, blood pressure and inflammation.

*Source: Fish in the Diet – A Review, British Nutrition Foundation, September 2013.

Delligent™ Technology showed better improvement of key lipid biomarkers in comparison to other tested reference supplements of omega-3 and lycopene, specifically in two key parameters related to cardiovascular health:

  • Lowering elevated triglyceride levels
Triglycerides level are reduced by 14% after 4 weeks of Lycodha supplementation, achieving double the reduction of the DHA control product with half the dose
  • Reducing LDL oxidation levels
Lycodha provides a significantly higher rate of reduction in LDL peroxidation in comparison with reference omega-3. After 4 weeks, Lycodha can reduce LDL-Px by as much as 86%.

Read more about the benefits of Lycodha with Delligent™ Technology here.